*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CY1685000
CHEMICAL NAME           : Benzeneacetic acid, alpha-methyl-4-(2-thiazolyloxy)-
CAS REGISTRY NUMBER     : 56355-17-0
BEILSTEIN REFERENCE NO. : 1128230
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H11-N-O3-S
MOLECULAR WEIGHT        : 249.30
WISWESSER LINE NOTATION : T5N CSJ BOR DY1&VQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * alpha-Methyl-4-(2-thiazolyloxy)benzeneacetic acid
   * Propionic acid, 2-(p-((2-thiazolyl)oxy)phenyl)-
   * 480156 S
   * 2-(4-(2-Thiazolyloxy)phenyl)propionic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 34,280,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 660 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 31,3424,1983
 
                            *** END OF RECORD ***