*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AC8756000
CHEMICAL NAME           : Acetamide,
                          N-(5,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxo-10-((phe
                          nylmethyl)thio)benzo( a) heptalen-7-yl)-, (S)-
CAS REGISTRY NUMBER     : 76129-12-9
BEILSTEIN REFERENCE NO. : 3185560
REFERENCE               : 4-14-00-00958 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C28-H29-N-O5-S
MOLECULAR WEIGHT        : 491.64
WISWESSER LINE NOTATION : L B677 MV&T&J CO1 DO1 ES1R& JMV1 NO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Colchicine, 10-(benzylthio)-10-demethoxy-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,636,1981
 
                            *** END OF RECORD ***