*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AD0700000
CHEMICAL NAME           : Acetamidine, N,N-dimethyl-2-(thymyloxy)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 20290-28-2
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H22-N2-O.Cl-H
MOLECULAR WEIGHT        : 270.84
WISWESSER LINE NOTATION : 1Y1&R D1 FO1YUM&N1&1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N,N-Dimethylthymyloxyacetamidine hydrochloride
   * Ethanimidamide, N,N-dimethyl-2-(5-methyl-2-(1-methylethyl)phenoxy)-,  
   monohydrochloride
   * SU-198 hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 99,353,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 46 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   AJDDAL American Journal of Digestive Diseases.  (New York, NY)  V.5-22,
   1938-55; New series: V.1-23, 1956-78.  For publisher information, see
   DDSCDJ.  Volume(issue)/page/year: 18,241,1951
 
                            *** END OF RECORD ***