*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AE1578000 CHEMICAL NAME : Acetanilide, 4'-chloro-2-(methyl(2-(pyrrolidinyl)ethyl)amino)-, dihydrochloride LAST UPDATED : 199012 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C15-H22-Cl-N3-O.2Cl-H MOLECULAR WEIGHT : 368.77 WISWESSER LINE NOTATION : T5NTJ A2N1&1VMR DG &GH 2 COMPOUND DESCRIPTOR : Drug Primary Irritant SYNONYMS/TRADE NAMES : * C 5418 * p-Chloro-2-(methyl(2-(pyrrolidinyl)ethyl)amino)acetanilide dihydrochloride *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 2% REACTION SEVERITY : Moderate REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,262,1959 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 77500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,262,1959 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 450 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,262,1959 *** END OF RECORD ***