*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AE3850000
CHEMICAL NAME           : Acetanilide, 4'-formyl-, 4'-(thiosemicarbazone)
CAS REGISTRY NUMBER     : 104-06-3
BEILSTEIN REFERENCE NO. : 2810335
REFERENCE               : 4-14-00-00075 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H12-N4-O-S
MOLECULAR WEIGHT        : 236.32
WISWESSER LINE NOTATION : SUYZMNU1R DMV1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Acetamide, N-(4-(((aminothioxomethyl)hydrazono)methyl)phenyl)-
   * p-Acetamidobenzaldehyde thiosemicarbazone
   * p-Acetaminobenzylidenethiosemicarbazone
   * p-Acetylaminobenzaldehyde thiosemicarbazone
   * Aktivan
   * Ambathizon
   * Amithiozone
   * Amitiozon
   * Antib
   * Benthiozone
   * Benzothiozane
   * Benzothiozon
   * Berculon A
   * Berkazon
   * Conteben
   * Diasan
   * Diazan
   * Domagk's T.B.1 conteben
   * Domakol
   * 4'-Formylacetanilide thiosemicarbazone
   * Ilbion
   * Livazone
   * Magk's T.B.1 conteben
   * Mivizon
   * Myvizone
   * Neotibil
   * Neustab
   * Novakol
   * Nuclon argentinian
   * Panrone
   * Parazone
   * 4207 RP
   * RP 4207
   * SDT 1041
   * Seroden
   * Siocarbazone
   * SQ 2321
   * TB I
   * TB I/698
   * TB 1 (Bayer)
   * Tebalon
   * Tebecure
   * Tebemar
   * Tebesone I
   * Tebethion
   * Tebethione
   * Tebezon
   * Thiacetazone
   * Thiacetone
   * Thiacetozone
   * Thibon
   * Thibone
   * Thioacetazon
   * Thioacetazone
   * Thiocarbazil
   * Thiomicid
   * Thionicid
   * Thioparamizon
   * Thioparamizone
   * Thiosemicarbarzone
   * Thiosemicarbazone (pharmaceutical)
   * Thiotebesin
   * Thiotebezin
   * Thiotebicina
   * Thizone
   * Tiacetazon
   * Tibicur
   * Tibion
   * Tibione
   * Tibizan
   * Tibon
   * Tibone
   * Tioacetazon
   * Tioatsetazon
   * Tiobicina
   * Tiocarone
   * Tiosecolo
   * Tubercazon
   * Tubigal
   * Tubin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 950 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 144,1310,1950
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 2,764,1950
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 3267 ug/kg
REFERENCE :
   NULSAK Nucleus (Calcutta).  (Dr. A.K. Sharma, Centre of Advanced Studies in
   Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta
   700 019, India)  V.1-    1958-  Volume(issue)/page/year: 22,96,1979
 
                            *** END OF RECORD ***