*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AE7175000
CHEMICAL NAME           : Acetanilide, 4',4'''-sulfonylbis-
CAS REGISTRY NUMBER     : 77-46-3
BEILSTEIN REFERENCE NO. : 2164071
REFERENCE               : 4-13-00-01361 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H16-N2-O4-S
MOLECULAR WEIGHT        : 332.40
WISWESSER LINE NOTATION : 1VMR DSWR DMV1
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * Acedapsone
   * Acetamide, N,N'-(sulfonyldi-4,1-phenylene)bis-
   * Acetamin
   * Atilon
   * BA 2650
   * Bis(p-acetamidophenyl) sulfone
   * Bis(4-acetamidophenyl)sulfone
   * Camilan
   * CI 556
   * Dadds
   * 4,4'-Diacetamidodiphenyl sulfone
   * 4,4'-Diacetylaminodiphenyl sulfone
   * Di-(p-acetylaminophenyl)sulfone
   * Diacetyldapsone
   * N,N'-Diacetyldapsone
   * N,N'-Diacetyl-4,4'-diaminodiphenyl sulfone
   * 4,4'-Diacetyldiaminodiphenyl sulfone
   * 1399 F
   * Hansolar
   * Rodilone
   * Sulfadiamine
   * Sulfodiamin
   * Sulfodiamine
   * Sulfone, bis(p-acetamidophenyl)
   * p,p'-Sulfonylbisacetanilide
   * 4,4'-Sulfonylbisacetanilide
   * 4',4'''-Sulfonylbis(acetanilide)
   * N,N'-(Sulfonyldi-4,1-phenylene)bisacetamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACSAT Journal of the American Chemical Society.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1879-  Volume(issue)/page/year: 61,617,1939
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4200 mg/kg/43W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Endocrine - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   24,149,1960
 
                            *** END OF RECORD ***