*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : CZ2200000 CHEMICAL NAME : 1,2-Benzenedicarboxamide CAS REGISTRY NUMBER : 88-96-0 BEILSTEIN REFERENCE NO. : 1868220 REFERENCE : 4-09-00-03265 (Beilstein Handbook Reference) LAST UPDATED : 199701 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C8-H8-N2-O2 MOLECULAR WEIGHT : 164.18 WISWESSER LINE NOTATION : ZVR BVZ COMPOUND DESCRIPTOR : Tumorigen Mutagen SYNONYMS/TRADE NAMES : * o-Carbamoylbenzamide * NCI-C03612 * P-D * Phthalamide * Phthaldiamide * o-Phthalic acid diamide *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4004 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 48,23,1990 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4104 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 48,23,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T1370 No. of Facilities: 111 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 111 (estimated) *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Negative: Carcinogenicity-mouse/rat EPA TSCA Section 8(b) CHEMICAL INVENTORY NCI Carcinogenesis Bioassay (feed);no evidence:mouse,rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. Volume(issue)/page/year: NCI-TR-161,79 *** END OF RECORD ***