*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CZ2230000
CHEMICAL NAME           : 1,3-Benzenedicarboxamide,
                          N,N'-bis(2,3-dihydroxypropyl)-5-((methoxyacetyl)amino
                          )-N-methyl- 2,4,6-triiodo-
CAS REGISTRY NUMBER     : 73334-07-3
BEILSTEIN REFERENCE NO. : 7085608
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C18-H24-I3-N3-O8
MOLECULAR WEIGHT        : 791.15
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Iopromide
   * SHL 414C
   * Ultravist
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 21403 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARASA5 Acta Radiologica, Supplementum.  (Acta Radiologica, POB 7449, S-10391
   Stockholm, Sweden) No.1-    1921-  Volume(issue)/page/year: 370,41,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 34 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AAJNDL AJNR, American Journal of Neuroradiology.  (Williams & Wilkins Co.,
   428 E. Preston St., Baltimore, MD 21202)  V.1-    1980-
   Volume(issue)/page/year: 4,350,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >21 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 44,1275,1994
 
                            *** END OF RECORD ***