*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DA9465480
CHEMICAL NAME           : Benzenesulfonamide,
                          4-amino-5-chloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2
                          -methoxy-
CAS REGISTRY NUMBER     : 68677-06-5
BEILSTEIN REFERENCE NO. : 0441632
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C14-H22-Cl-N3-O3-S
MOLECULAR WEIGHT        : 347.90
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4-Amino-5-chloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzenesulf
     onamide
   * Lorapride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4225611
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4225611
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 130 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4225611
 
                            *** END OF RECORD ***