*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DA9520000
CHEMICAL NAME           : Benzenesulfonamide,
                          4-amino-N-(1-phenyl-1H-pyrazol-5-yl)-
CAS REGISTRY NUMBER     : 526-08-9
BEILSTEIN REFERENCE NO. : 0308518
REFERENCE               : 5-25-09-00415 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C15-H14-N4-O2-S
MOLECULAR WEIGHT        : 314.39
WISWESSER LINE NOTATION : T5NNJ BR& CMSWR DZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(p-Aminobenzenesulfonamido)-2-phenylpyrazole
   * 4-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
   * Depocid
   * Depotsulfonamide
   * Eftolon
   * Firmazolo
   * Inamil
   * Isarol
   * Merian
   * Microtan pirazolo
   * Orisul
   * Orisulf
   * Paidazolo
   * N'-(1-Phenylpyrazol-5-yl)sulfanilamide
   * N(sup 1)-(1-Phenylpyrazol-5-yl)sulfanilamide
   * 1-Phenyl-5-sulfanilamidopyrazole
   * Plisulfan
   * Raziosulfa
   * SP
   * SPP
   * Sulfabid
   * Sulfafenazolo
   * Sulfanilamide, N(sup 1)-(1-phenylpyrazol-5-yl)-
   * 5-Sulfanilamido-1-phenylpyrazole
   * Sulfaphenazole
   * Sulfaphenazon
   * Sulfaphenylpipazol
   * Sulfaphenylpyrazole
   * Sulphenazole
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,387,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 525 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,387,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3016 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MIMEAO Minerva Medica.  (Edizioni Minerva Medica, Casella Postale 491,
   I-10126 Turin, Italy) V.1-    1909-  Volume(issue)/page/year: 52,1789,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 660 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,387,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 470 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,387,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 950 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,387,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 440 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,387,1982
 
                            *** END OF RECORD ***