*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DB5250000
CHEMICAL NAME           : Benzenesulfonic acid, 4-chloro-, 4-chlorophenyl ester
CAS REGISTRY NUMBER     : 80-33-1
BEILSTEIN REFERENCE NO. : 2944674
REFERENCE               : 4-11-00-00109 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C12-H8-Cl2-O3-S
MOLECULAR WEIGHT        : 303.16
WISWESSER LINE NOTATION : GR DSWOR DG
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Tumorigen
SYNONYMS/TRADE NAMES :
   * Acaricydol E 20
   * C 1,006
   * CCS
   * Chloorfenson
   * (4-Chloor-fenyl)-4-chloor-benzeen-sulfonaat
   * Chlorefenizon
   * Chlorfenson
   * p-Chlorfenylester kyseliny p-chlorbenzensulfonove
   * 4-Chlorobenzenesulfonate de 4-chlorophenyle
   * p-Chlorobenzenesulfonic acid, p-chlorophenyl ester
   * Chlorofenizon
   * Chlorofenson
   * p-Chlorophenyl p-chlorobenzenesulfonate
   * 4-Chlorophenyl 4-chlorobenzenesulfonate
   * p-Chlorophenyl p-chlorobenzenesulphonate
   * 4-Chlorophenyl 4-chlorobenzenesulphonate
   * 4-Chlorphenyl-4'-chlorbenzolsulfonat
   * (4-Chlor-phenyl)-4-chlor-benzol-sulfonate
   * (4-Cloro-fenil)-4-cloro-venzol-solfonato
   * Corotran
   * CPCBS
   * D 854
   * ENT 16,358
   * Ephirsulphonate
   * Ester sulfonate
   * Estonmite
   * Ethersulfonate
   * Genite 883
   * K 6451
   * Lethalaire G-58
   * Miticide K-101
   * Niagaratran
   * Onex
   * Orthotran
   * Otracid
   * Ovatran
   * Ovochlor
   * Ovotox
   * Ovotran
   * Parachlorophenyl-parachlorobenzene-sulfonate
   * Pcpcbs
   * Sappilan
   * Trichlorfenson (Obs.)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,381,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PEMNDP Pesticide Manual.  (The British Crop Protection Council, 20 Bridport
   Rd., Thornton Heath CR4 7QG, UK)  V.1-    1968-  Volume(issue)/page/year:
   8,150,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2050 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DABBBA Dissertation Abstracts International, B: The Sciences and
   Engineering.  (University Microfilms International, 300 N. Zeeb Rd., Ann
   Arbor, MI 48106)  V.30-    1969-  Volume(issue)/page/year: 32,4116,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1475 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,37,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5660 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,841,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 640 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,841,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : 3780 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,841,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : 4600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PEMNDP Pesticide Manual.  (The British Crop Protection Council, 20 Bridport
   Rd., Thornton Heath CR4 7QG, UK)  V.1-    1968-  Volume(issue)/page/year:
   8,150,1987
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1008 mg/kg/12W-C
TOXIC EFFECTS :
   Liver - changes in liver weight
   Endocrine - changes in thyroid weight
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation,
   etc.)
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 1,113,1973
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 115 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Blood - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-159

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   RREVAH Residue Reviews.  (Springer-Verlag New York, Inc., Service Center, 44
   Hartz Way, Secaucus, NJ 07094)  V.1-    1962-  Volume(issue)/page/year:
   56,107,1975

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-RUSSIA:STEL 2 mg/m3 JAN 1993

 
                            *** END OF RECORD ***