*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DB5500000
CHEMICAL NAME           : Benzenesulfonic acid,
                          5-chloro-2-((2-hydroxy-1-naphthalenyl)azo)-4-methyl-,
                          barium salt
CAS REGISTRY NUMBER     : 5160-02-1
OTHER CAS REGISTRY NOS. : 12237-52-4
                          12238-39-0
                          12238-41-4
                          12238-43-6
                          24777-23-9
                          52627-68-6
                          68894-03-1
LAST UPDATED            : 199710
DATA ITEMS CITED        : 17
MOLECULAR FORMULA       : C17-H12-Cl-N2-O4-S.1/2Ba
MOLECULAR WEIGHT        : 444.49
WISWESSER LINE NOTATION : L66J BNUNR DG C FSWQ& CQ & 2-BA-
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Astro Orange
   * Atomic Red
   * Brilliant Red
   * Brilliant Scarlet CA
   * Brilliant Scarlet CBA
   * Brilliant Scarlet CTA
   * Brilliant Toner Z
   * Bronze Red RO
   * Bronze Red 16913 Yellowish
   * Bronze Scarlet
   * Bronze Scarlet C
   * Bronze Scarlet CA
   * Bronze Scarlet CBA
   * Bronze Scarlet CT
   * Bronze Scarlet CTA
   * Bronze Scarlet Toner
   * Carnation Red
   * 5-Chloro-2-((2-hydroxy-1-naphthalenyl)azo)-4-methylbenzenesulfonic acid,  
   barium salt (2:1)
   * 5-Chloro-2-((2-hydroxy-1-naphthalenyl)azo)-4-methylbenzenesulphonic acid, 
    barium salt
   * 5-Chloro-2-((2-hydroxy-1-naphthyl)azo)-p-toluenesulfonic acid, barium  
   salt
   * 1-(4-Chloro-o-sulfo-5-tolylazo)-2-naphthol, barium salt
   * 1-(4-Chloro-o-sulpho-5-tolylazo)-2-naphthol, barium salt
   * C.I. 15585:1
   * C.I. Pigment Red 53:1
   * C.I. Pigment Red 53, barium salt
   * Cosmetic Coral Red KO Bluish
   * Cosmetic DVR
   * Cosmetic Pigment Yellow Red DVR
   * Dainichi Lake Red C
   * D and C Red No. 9
   * Desert Red
   * Duplex Red Lake C20-5925
   * Eljon Lake Red C
   * Hamilton Red
   * Helio Red Toner LCLL
   * Irgalite Red CBN
   * Irgalite Red CBR
   * Irgalite Red CBT
   * Irgalite Red MBC
   * Isol Lake Red LCS 12527
   * Isol Red LCR 2517
   * Lake Red 1520
   * Lake Red C
   * Lake Red C 18287
   * Lake Red C 21245
   * Lake Red C 27200
   * Lake Red C 27217
   * Lake Red C 27218
   * Lake Red C Barium Toner
   * Lake Red CC
   * Lake Red CCT
   * Lake Red CR
   * Lake Red CRLC-232 (barium)
   * Lake Red C Toner 8195
   * Lake Red C Toner 8366
   * Lake Red GB barium salt
   * Lake Red RRG
   * Lake Red Toner C
   * Lake Red Toner LCLL
   * Latexol Scarlet R
   * Latexol Scarlet R Solupowder
   * Ld Rubber Red 16913
   * Lutetia Red CLN
   * Lutetia Red CLN-ST
   * Microtex Lake Red CR
   * Mohican Red A-8008
   * NCI-C53792
   * No.3 Conc. Bronze Scarlet
   * No.3 Conc. Scarlet
   * Paridine Red LCL
   * Pigment Lake Red BFC
   * Pigment Lake Red CD
   * Pigment Lake Red LC
   * Pigment Red 53:1
   * Pigment Red CD
   * Potomac Red
   * Recolite Red Lake C
   * Recolite Red Lake CR
   * 1860 Red
   * Red 1860
   * Red For Lake C
   * Red For Lake C Toner RA-5190
   * Red For Lake Toner RA-5190
   * Red 16913H
   * Red Lake C
   * Red Lake CM 20-5650
   * Red Lake CR-1
   * Red Lake C Toner
   * Red Lake C Toner 20-5650
   * Red Lake C Toner RA-5190
   * Red Lake R-91
   * Red Scarlet
   * Red Toner Z
   * Rubber Red 16913R
   * Sanyo Lake Red C
   * Scarlet Toner Y
   * Segnale Red LC
   * Segnale Red LCG
   * Segnale Red LCL
   * Sico Lake Red 2L
   * Superol Red C RT-265
   * Symuler Lake Red C
   * Termosolido Red LCG
   * Texan Red Toner D
   * Toner Lake Red C
   * Transparent Bronze Scarlet
   * Vulcafix Scarlet R
   * Vulcafix Scarlet R-D masse
   * Vulcafor Red 2R
   * Vulcan Red LC
   * Vulcol Fast Red L
   * Wayne Red X-2486
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 27300 mg/kg/91D-C
TOXIC EFFECTS :
   Liver - other changes
   Related to Chronic Data - death
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-225,1982
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 546 gm/kg/2Y-C
TOXIC EFFECTS :
   Endocrine - changes in spleen weight
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   4,200,1962
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 21 gm/kg/14D-C
TOXIC EFFECTS :
   Related to Chronic Data - death
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-225,1982
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 130 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
   Blood - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-225,1982
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 109 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Blood - tumors
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   25,619,1987
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   236,933,1987

                              *** REVIEWS ***
 
   IARC Cancer Review:Animal Limited Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 57,203,1993

   IARC Cancer Review:Animal Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 8,107,1975

   IARC Cancer Review:Human No Adequate Data
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 8,107,1975

   IARC Cancer Review:Human Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 57,203,1993

   IARC Cancer Review:Group 3
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 57,203,1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M3849
       No. of Facilities: 1160 (estimated)
       No. of Industries: 15
       No. of Occupations: 21
       No. of Employees: 14370 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M3849
       No. of Facilities: 8245 (estimated)
       No. of Industries: 43
       No. of Occupations: 49
       No. of Employees: 122313 (estimated)
       No. of Female Employees: 23095 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NTP Carcinogenesis Bioassay (feed);clear evidence:rat
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-225,82

   NTP Carcinogenesis Bioassay (feed);no evidence:mouse
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-225,82

 
                            *** END OF RECORD ***