*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DB7000000
CHEMICAL NAME           : Benzenesulfonic acid,
                          p-((4-(5-((2-hydroxyethyl)sulfonyl)-2-methoxyphenyl)a
                          zo)-5-hydroxy-
                          3-methylpyrazol-1-yl)-3-chloro-5-methyl-, hydrogen
                          sulfate (ester), disodium salt
CAS REGISTRY NUMBER     : 18976-74-4
LAST UPDATED            : 198910
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C20-H19-Cl-N4-O11-S3.2Na
MOLECULAR WEIGHT        : 669.04
WISWESSER LINE NOTATION : T5NNJ AR CO1 FSW2OSWO DNUNR BG F1 DSWO&& C1 EQ &-NA-
                          2 &50/21 &50/38
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * C.I. Reactive Yellow 14
   * Procion Yellow MX 4R
   * Remazol Yellow G
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 52 gm/kg/58W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Skin and Appendages - tumors
REFERENCE :
   TKORAS Trudy Kazakhskogo Nauchno-Issledovatel'skogo Instituta Onkologii i
   Radiologii.  Transactions of the Kazakh Scientific Research Institute of
   Oncology and Radiology.  (Kazakhskii Nauchno- Issledovatel'skii Institut
   Onkologii i Radiologii, Alma-Ata, USSR)  V.1-    1965-
   Volume(issue)/page/year: 3,53,1967
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 25 gm/kg/81W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
REFERENCE :
   TKORAS Trudy Kazakhskogo Nauchno-Issledovatel'skogo Instituta Onkologii i
   Radiologii.  Transactions of the Kazakh Scientific Research Institute of
   Oncology and Radiology.  (Kazakhskii Nauchno- Issledovatel'skii Institut
   Onkologii i Radiologii, Alma-Ata, USSR)  V.1-    1965-
   Volume(issue)/page/year: 3,53,1967
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 38 gm/kg/32W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Skin and Appendages - tumors
REFERENCE :
   TKORAS Trudy Kazakhskogo Nauchno-Issledovatel'skogo Instituta Onkologii i
   Radiologii.  Transactions of the Kazakh Scientific Research Institute of
   Oncology and Radiology.  (Kazakhskii Nauchno- Issledovatel'skii Institut
   Onkologii i Radiologii, Alma-Ata, USSR)  V.1-    1965-
   Volume(issue)/page/year: 3,53,1967
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 gm/kg/1Y-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Skin and Appendages - tumors
REFERENCE :
   TKORAS Trudy Kazakhskogo Nauchno-Issledovatel'skogo Instituta Onkologii i
   Radiologii.  Transactions of the Kazakh Scientific Research Institute of
   Oncology and Radiology.  (Kazakhskii Nauchno- Issledovatel'skii Institut
   Onkologii i Radiologii, Alma-Ata, USSR)  V.1-    1965-
   Volume(issue)/page/year: 3,53,1967
 
                            *** END OF RECORD ***