*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DC3000000
CHEMICAL NAME : Benzene, 1,2,4-trimethoxy-5-propenyl-, (Z)-
CAS REGISTRY NUMBER : 5273-86-9
BEILSTEIN REFERENCE NO. : 1910605
REFERENCE : 3-06-00-06440 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C12-H16-O3
MOLECULAR WEIGHT : 208.28
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* beta-Asarone
* cis-Asarone
* cis-beta-Asarone
* (Z)-Asarone
* Benzene, 1,2,4-trimethoxy-5-(1-propenyl)-, (Z)-
* cis-Isoasarone
* cis-Isoelemicin
* (Z)-5-Propenyl-1,2,4-trimethoxybenzene
* (Z)-1,2,4-Trimethoxy-5-(1-propenyl)benzene
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 52 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Liver - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
47,2275,1987
** MUTATION DATA **
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Human Lymphocyte
DOSE/DURATION : 107 mg/L
REFERENCE :
PLMEAA Planta Medica. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart
1, Fed. Rep. Ger.) V.1- 1953- Volume(issue)/page/year: 53,251,1987
TYPE OF TEST : Sister chromatid exchange
TEST SYSTEM : Human Lymphocyte
DOSE/DURATION : 107 mg/L
REFERENCE :
PLMEAA Planta Medica. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart
1, Fed. Rep. Ger.) V.1- 1953- Volume(issue)/page/year: 53,251,1987
TYPE OF TEST : Unscheduled DNA synthesis
TEST SYSTEM : Rodent - rat Liver
DOSE/DURATION : 500 umol/L
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
32,223,1994
*** END OF RECORD ***