*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DC3750000
CHEMICAL NAME           : Benzene,
                          1,3,5-trimethyl-2,4,6-tris(3,5-di-t-butyl-4-hydroxybe
                          nzyl)-
CAS REGISTRY NUMBER     : 1709-70-2
OTHER CAS REGISTRY NOS. : 99346-90-4
BEILSTEIN REFERENCE NO. : 2034522
LAST UPDATED            : 199710
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C54-H78-O3
MOLECULAR WEIGHT        : 775.32
WISWESSER LINE NOTATION : 1X1&1&R BQ CX1&1&1 E1R B1 D1 F1 C1R DQ CX1&1&1
                          EX1&1&1 E1R DQ CX1&1&1 EX1&1&1
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Ahydol
   * Antioxidant 330
   * AO-40
   * Ethanox 330
   * Santoquin emulsion
   * Santoquin mixture 6
   * 1,3,5-Trimethyl-2,4,6-tris(3,5-di-tert-butyl-4-hydroxybenzyl)benzene
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IPSTB3 International Polymer Science and Technology.  (Rapra Technology
   Ltd., Shawbury, Shrewsbury, Shropshire SY4 4NR, UK) Volume(issue)/page/year:
   3,93,1976
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 21 gm/kg/44W-I
TOXIC EFFECTS :
   Liver - liver function tests impaired
   Kidney, Ureter, Bladder - other changes in urine composition
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 43(9),31,1978
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1100 mg/kg
SEX/DURATION            : female 1-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 43(9),31,1978

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - T0345
       No. of Facilities: 21 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 83 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - T0345
       No. of Facilities: 1097 (estimated)
       No. of Industries: 19
       No. of Occupations: 26
       No. of Employees: 29536 (estimated)
       No. of Female Employees: 12132 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***