*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DD2100000
CHEMICAL NAME           : Benzilic acid, 4,4'-dibromo-, isopropyl ester
CAS REGISTRY NUMBER     : 18181-80-1
OTHER CAS REGISTRY NOS. : 39394-17-7
BEILSTEIN REFERENCE NO. : 2152560
LAST UPDATED            : 199710
DATA ITEMS CITED        : 11
MOLECULAR FORMULA       : C17-H16-Br2-O3
MOLECULAR WEIGHT        : 428.15
WISWESSER LINE NOTATION : ER DXQR DE&VOY1&1
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Mutagen
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Acarol
   * Ascarol 2E
   * Benzeneacetic acid, 4-bromo-alpha-(4-bromophenyl)-alpha-hydroxy-,  
   1-methylethyl ester
   * 4-Bromo-alpha-(4-bromophenyl)-alpha-hydroxybenzeneacetic acid 1-methyl  
   ethyl ester
   * Bromopropylate
   * Ciba-Geigy GS 19851
   * 4,4'-Dibromobenzilic acid isopropyl ester
   * ENT 27552
   * Folbex VA
   * Geigy GS-19851
   * GS-19851
   * Isopropyl 4,4'-dibromobenzilate
   * 1-Methylethyl 4-bromo-alpha-(4-bromophenyl)-alpha-hydroxybenzeneacetate
   * Neoron
   * NSC 195087
   * Phenisobromolate
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Open irritation test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 121 mg
REACTION SEVERITY       : Moderate
REFERENCE :
   CIGET* Ciba-Geigy Toxicology Data/Indexes.  (Ciba-Geigy Corp., 556 Morris
   Ave., Summit, NJ 07901)  Volume(issue)/page/year: -,-,1977
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 600 ug
REACTION SEVERITY       : Mild
REFERENCE :
   CIGET* Ciba-Geigy Toxicology Data/Indexes.  (Ciba-Geigy Corp., 556 Morris
   Ave., Summit, NJ 07901)  Volume(issue)/page/year: -,-,1977
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BESAAT Bulletin of the Entomological Society of America.  (Entomological
   Soc. of America, 4603 Calvert Rd., College Park, MD 20740)  V.1-    1955-
   Volume(issue)/page/year: 15,97,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PEMNDP Pesticide Manual.  (The British Crop Protection Council, 20 Bridport
   Rd., Thornton Heath CR4 7QG, UK)  V.1-    1968-  Volume(issue)/page/year:
   9,99,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College
   Science Pub., 1969  Volume(issue)/page/year: 5,29,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 10200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CIGET* Ciba-Geigy Toxicology Data/Indexes.  (Ciba-Geigy Corp., 556 Morris
   Ave., Summit, NJ 07901)  Volume(issue)/page/year: -,-,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd,
   eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year:
   A552,1985
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Morphological transformation
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 4620 mg/kg/77D (Continuous)
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 11,1413,1990
 
TYPE OF TEST            : Unscheduled DNA synthesis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 125 mg/kg
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 17,407,1996

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   RREVAH Residue Reviews.  (Springer-Verlag New York, Inc., Service Center, 44
   Hartz Way, Secaucus, NJ 07094)  V.1-    1962-  Volume(issue)/page/year:
   56,107,1975

                          *** STATUS IN U.S. ***
 
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***