*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DD2480000
CHEMICAL NAME           : Benzilic acid, 2-(diethylamino)ethyl ester
CAS REGISTRY NUMBER     : 302-40-9
BEILSTEIN REFERENCE NO. : 2156821
REFERENCE               : 4-10-00-01263 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C20-H25-N-O3
MOLECULAR WEIGHT        : 327.46
WISWESSER LINE NOTATION : QXR&R&VO2N2&2
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
                          Human
SYNONYMS/TRADE NAMES :
   * Benactyzin
   * Benactizina
   * Benactyzine
   * Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 2-(diethylamino)ethyl  
   ester
   * Benzilic acid beta-diethylaminoethyl ester
   * Diazil
   * Diethylaminoethyl benzilate
   * beta-Diethylaminoethyl benzilate
   * 2-(Diethylamino)ethyl benzilate
   * 2-(Diethylamino)ethyl diphenylglycolate
   * Diphenylglycolic acid 2-(diethylamino)ethyl ester
   * alpha-Hydroxy-alpha-phenylbenzeneacetic acid 2-(diethylamino)ethyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Human
DOSE/DURATION           : 100 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
REFERENCE :
   85IVAW "Possible Long-Term Health Effects of Short-Term Exposure to Chemical
   Agents," National Research Council, 3 vols., Washington, DC, National
   Academy Press, 1982-85  Volume(issue)/page/year: 1,L1,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD-A099-745
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   111,293,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 159 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 32,311,1969
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - hamster
DOSE/DURATION           : 10 mg/kg
REFERENCE :
   ACNSAX Activitas Nervosa Superior.  (Avicenum, Malostranske nam. 28, Prague
   1, Czechoslovakia) V.1-    1959-  Volume(issue)/page/year: 17,253,1975
 
                            *** END OF RECORD ***