*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DB2680000
CHEMICAL NAME           : Benzenesulfonamide, p-(N-hydroxyamidino)-,
                          hydrochloride
LAST UPDATED            : 198709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C7-H9-N3-O3-S.Cl-H
MOLECULAR WEIGHT        : 251.71
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * p-(N-Hydroxyamidino)benzenesulfonamide hydrochloride
   * p-Sulphonamidobenzamidoxime hydrochloride
   * V 186
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 2360 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 84,160,1945
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 738 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 84,160,1945
 
                            *** END OF RECORD ***