*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DD3505000
CHEMICAL NAME : Benzilic acid, 1-ethyl-3-piperidyl ester
CAS REGISTRY NUMBER : 3567-12-2
BEILSTEIN REFERENCE NO. : 0309916
REFERENCE : 4-21-00-00029 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C21-H25-N-O3
MOLECULAR WEIGHT : 339.47
WISWESSER LINE NOTATION : T6MTJ COVXQR&R& C2
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 1-ethyl-3-piperidinyl
ester
* Ditran JB 318
* EPB
* N-Ethyl-3-piperidyl benzilate
* JB 318
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 25 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness
Behavioral - ataxia
Cardiac - pulse rate increase, without fall in BP
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 120,186,1959
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 34 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness
Behavioral - ataxia
Cardiac - pulse rate increase, without fall in BP
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 120,186,1959
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 19 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness
Behavioral - ataxia
Cardiac - pulse rate increase, without fall in BP
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 120,186,1959
*** END OF RECORD ***