*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DB2733000
CHEMICAL NAME           : Benzenesulfonamide,
                          5-(1-hydroxy-2-((2-(2-methoxyphenoxy)ethyl)amino)ethy
                          l)-2-methyl-, monohydrochloride
CAS REGISTRY NUMBER     : 70958-86-0
LAST UPDATED            : 199604
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H24-N2-O5-S.Cl-H
MOLECULAR WEIGHT        : 416.96
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * YM-09538
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 210 mg/kg
SEX/DURATION            : female 15-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - stillbirth
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 34,351,1987
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 7 gm/kg
SEX/DURATION            : female 15-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - live birth index (measured after birth)
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 34,351,1987
 
                            *** END OF RECORD ***