*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DD4550000
CHEMICAL NAME           : Benzilic acid, 3-piperidyl ester
CAS REGISTRY NUMBER     : 57258-61-4
BEILSTEIN REFERENCE NO. : 1393868
REFERENCE               : 5-21-01-00028 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H21-N-O3
MOLECULAR WEIGHT        : 311.41
WISWESSER LINE NOTATION : T6MTJ COVXQR&R
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * JB 841
   * 3-Piperidyl benzilate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - ataxia
   Cardiac - pulse rate increase, without fall in BP
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,186,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - ataxia
   Cardiac - pulse rate increase, without fall in BP
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,186,1959
 
                            *** END OF RECORD ***