*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DD6505000
CHEMICAL NAME           : 2-Benzimidazolecarbamic acid, methyl ester,
                          hydrochloride
CAS REGISTRY NUMBER     : 23424-47-7
LAST UPDATED            : 199603
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C9-H9-N3-O2.xCl-H
MOLECULAR WEIGHT        : 446.43
SYNONYMS/TRADE NAMES :
   * Carbamic acid, 1H-benzimidazol-2-yl-, methyl ester, hydrochloride
   * Carbendazim hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 12500 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(10),73,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9 gm/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(10),73,1987
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 910 mg/kg/26W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - proteinuria
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(10),73,1987
 
                            *** END OF RECORD ***