*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DD6520300
CHEMICAL NAME           : 2-Benzimidazolecarbamic acid, N-nitroso-, methyl
                          ester
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C9-H7-N5-O4
MOLECULAR WEIGHT        : 249.21
WISWESSER LINE NOTATION : T56 BN DNJ BNO CNNO&VO1
COMPOUND DESCRIPTOR     : Tumorigen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Carbendazime and sodium nitrite (1:1)
   * 2-Methyl-N-nitroso-benzimidazole carbamate and sodium nitrite (1:1)
   * Sodium nitrite and carbendazime (1:1)
   * Sodium nitrite and 2-methyl-N-nitroso-benzimidazole carbamate (1:1)
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4200 mg/kg
                          female 8-14 day(s) after conception
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Reproductive - Tumorigenic effects - transplacental tumorigenesis
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   MGONAD Magyar Onkologia. Hungarian Oncology.  (Kultura, POB 149, H-1389
   Budapest, Hungary) V.1-    1957-  Volume(issue)/page/year: 20,163,1976
 
                            *** END OF RECORD ***