*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DE0456000 CHEMICAL NAME : 2-Benzimidazolepropionic acid, alpha-amino-5-(bis(2-chloroethyl)amino)-1-phenyl-, (+-)- CAS REGISTRY NUMBER : 32021-40-2 BEILSTEIN REFERENCE NO. : 4019059 REFERENCE : 5-25-17-00018 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C20-H22-Cl2-N4-O2 MOLECULAR WEIGHT : 421.36 WISWESSER LINE NOTATION : T56 BN DNJ BR& C1YZVQ GN2G2G COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * (+-)-alpha-Amino-5-(bis(2-chloroethyl)amino)-1-phenyl-2-benzimidazolepro pionic acid * (+-)-alpha-Amino-5-(bis(2-chloroethyl)amino)-1-phenyl-1H-benzimidazole-2 -propanoic acid * IMET 3164 * beta-(1-Phenyl-5-bis-(beta-chloroethyl)amino-2-benzimidazolyl)-DL-alanine * Zimet-3164 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 282 mg/kg TOXIC EFFECTS : Blood - changes in spleen Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation REFERENCE : AGACBH Agents and Actions, A Swiss Journal of Pharmacology. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1969/70- Volume(issue)/page/year: 9,521,1979 *** END OF RECORD ***