*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE0456000
CHEMICAL NAME           : 2-Benzimidazolepropionic acid,
                          alpha-amino-5-(bis(2-chloroethyl)amino)-1-phenyl-,
                          (+-)-
CAS REGISTRY NUMBER     : 32021-40-2
BEILSTEIN REFERENCE NO. : 4019059
REFERENCE               : 5-25-17-00018 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H22-Cl2-N4-O2
MOLECULAR WEIGHT        : 421.36
WISWESSER LINE NOTATION : T56 BN DNJ BR& C1YZVQ GN2G2G
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (+-)-alpha-Amino-5-(bis(2-chloroethyl)amino)-1-phenyl-2-benzimidazolepro
     pionic acid
   *   (+-)-alpha-Amino-5-(bis(2-chloroethyl)amino)-1-phenyl-1H-benzimidazole-2
     -propanoic acid
   * IMET 3164
   * beta-(1-Phenyl-5-bis-(beta-chloroethyl)amino-2-benzimidazolyl)-DL-alanine
   * Zimet-3164
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 282 mg/kg
TOXIC EFFECTS :
   Blood - changes in spleen
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   AGACBH Agents and Actions, A Swiss Journal of Pharmacology.  (Birkhaeuser
   Verlag, POB 133, CH-4010 Basel, Switzerland)  V.1-    1969/70-
   Volume(issue)/page/year: 9,521,1979
 
                            *** END OF RECORD ***