*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE1800000
CHEMICAL NAME           : 2-Benzimidazolinone,
                          5-chloro-1-(3-(dimethylamino)propyl)-3-phenyl-
CAS REGISTRY NUMBER     : 4755-59-3
BEILSTEIN REFERENCE NO. : 0894387
REFERENCE               : 5-24-02-00399 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C18-H20-Cl-N3-O
MOLECULAR WEIGHT        : 329.86
WISWESSER LINE NOTATION : T6MTJ DXQR&R
SYNONYMS/TRADE NAMES :
   * AW-14-2446
   * 2H-Benzimidazol-2-one,  
   5-chloro-1-(3-(dimethylamino)propyl)-1,3-dihydro-3-phenyl-
   * 5-Chloro-1-(3-(dimethylamino)propyl)-3-phenyl-2-benzimidazolinone
   * Clodazone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   INPHB6 International Pharmacopsychiatry.  (Basel, Switzerland)  V.1-17,
   1968-72.  Volume(issue)/page/year: 1,214,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 142 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   INPHB6 International Pharmacopsychiatry.  (Basel, Switzerland)  V.1-17,
   1968-72.  Volume(issue)/page/year: 1,214,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 77 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   INPHB6 International Pharmacopsychiatry.  (Basel, Switzerland)  V.1-17,
   1968-72.  Volume(issue)/page/year: 1,214,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 715 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   INPHB6 International Pharmacopsychiatry.  (Basel, Switzerland)  V.1-17,
   1968-72.  Volume(issue)/page/year: 1,214,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   INPHB6 International Pharmacopsychiatry.  (Basel, Switzerland)  V.1-17,
   1968-72.  Volume(issue)/page/year: 1,214,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 505 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   INPHB6 International Pharmacopsychiatry.  (Basel, Switzerland)  V.1-17,
   1968-72.  Volume(issue)/page/year: 1,214,1968
 
                            *** END OF RECORD ***