*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE3150000
CHEMICAL NAME           : 1H-Benz(e)indolium,
                          2-(7(1,1-dimethyl-3-(4-sulfobutyl)benz(e)indolin-2-yl
                          idene)-
                          1,3,5-heptatrienyl)-1,1-dimethyl-3-(4-sulfobutyl)-,
                          hydroxide, inner salt, sodium salt
CAS REGISTRY NUMBER     : 3599-32-4
LAST UPDATED            : 199806
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C43-H48-N2-O6-S2.Na
MOLECULAR WEIGHT        : 776.04
WISWESSER LINE NOTATION : T C5 B66 FKJ D4SWQ F1 F1 E1U2U2U2- ET C5 B66 FKJ
                          D4SWQ F1 F1 &Q 2 &-NA-
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4,5-Benzoindotricarbocyanine
   * Cardio-green
   * ICG
   * Indocyanine Green
   * HWD Indocyanine Green
   * NK 1611
   * IR 125
   * Ujoviridin
   * Wofaverdin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 87 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,189,1995
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   44,225,1978

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M1558
       No. of Facilities: 57 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 172 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***