*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE4080500
CHEMICAL NAME           : 1H-Benz(de)isoquinoline-2(3H)-acetic acid, 1,3-dioxo-
CAS REGISTRY NUMBER     : 51411-04-2
BEILSTEIN REFERENCE NO. : 0244370
REFERENCE               : 4-21-00-05562 (Beilstein Handbook Reference)
LAST UPDATED            : 199703
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C14-H9-N-O4
MOLECULAR WEIGHT        : 255.24
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Alrestatin
   * AY 22284
   * 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-acetic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4405625
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1380 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4118495
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1220 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4118495
 
                            *** END OF RECORD ***