*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE4155000
CHEMICAL NAME           : 1,2-Benzisothiazole, 3-(allyloxy)-, 1,1-dioxide
CAS REGISTRY NUMBER     : 27605-76-1
BEILSTEIN REFERENCE NO. : 1214464
LAST UPDATED            : 199612
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C10-H9-N-O3-S
MOLECULAR WEIGHT        : 223.26
WISWESSER LINE NOTATION : T56 BSWNJ DO2U1
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Drug
SYNONYMS/TRADE NAMES :
   * 3-(Allyloxy)-1,2-benzisothiazole 1,1-dioxide
   * 1,2-Benzisothiazole, 3-(2-propenyloxy)-, 1,1-dioxide
   * Oryzaemate
   * Oryzemate
   * PO-20
   * Probenazole
   * 3-(2-Propenyloxy)-1,2-benzisothiazole 1,1-dioxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2030 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NNGADV Nippon Noyaku Gakkaishi.  Journal of the Pesticide Science Society of
   Japan.  (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170,
   Japan)  V.1-    1976-  Volume(issue)/page/year: 7,307,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 850 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 13,219,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPIFAN Japan Pesticide Information.  (Japan Plant Protection Assoc.,
   1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan)  No.1-61, 1969-92.  For
   publisher information, see AGJAEP.  Volume(issue)/page/year: (37),37,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2750 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - ataxia
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 13,205,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 745 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 13,205,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPIFAN Japan Pesticide Information.  (Japan Plant Protection Assoc.,
   1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan)  No.1-61, 1969-92.  For
   publisher information, see AGJAEP.  Volume(issue)/page/year: (37),37,1980
 
                            *** END OF RECORD ***