*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE4250000
CHEMICAL NAME           : 1,2-Benzisothiazolin-3-one, 1,1-dioxide, calcium salt
CAS REGISTRY NUMBER     : 6485-34-3
LAST UPDATED            : 199701
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C14-H10-N2-O6-S2.Ca
MOLECULAR WEIGHT        : 406.46
WISWESSER LINE NOTATION : T56 BSWNVJ 2 &-CA-
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, calcium salt
   * Calcium o-benzosulfimide
   * Calcium o-benzosulphimide
   * Calcium 2-benzosulphimide
   * Calcium saccharin
   * Calcium saccharina
   * Calcium saccharinate
   * Saccharin calcium
   * Sulphobenzoic imide calcium salt
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 100 mg/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   40,4541,1980
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 8 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 163,63,1986

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X1558
       No. of Facilities: 86 (estimated)
       No. of Industries: 2
       No. of Occupations: 3
       No. of Employees: 1017 (estimated)
       No. of Female Employees: 777 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   NTP 7th Annual Report on Carcinogens, 1992 : anticipated to be carcinogen

 
                            *** END OF RECORD ***