*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE5376000
CHEMICAL NAME           : 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline,
                          6,7,7a,8-tetrahydro-9,10-dimethoxy- 7-methyl-, (R)-
CAS REGISTRY NUMBER     : 25127-29-1
LAST UPDATED            : 199206
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H21-N-O4
MOLECULAR WEIGHT        : 339.42
SYNONYMS/TRADE NAMES :
   * Aporphine, 8,9-dimethoxy-1,2-(methylenedioxy)-
   * Crebanin
   * Crebanine
   * 8,9-Dimethoxy-1,2-(methylenedioxy)aporphine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 89470 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - irritability
   Lungs, Thorax, or Respiration - respiratory obstruction
REFERENCE :
   CTYAD8 Zhongcaoyao.  Chinese Traditional and Herbal Medicine.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-
      1980-  Volume(issue)/page/year: 20,422,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 24230 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - irritability
   Lungs, Thorax, or Respiration - respiratory obstruction
REFERENCE :
   CTYAD8 Zhongcaoyao.  Chinese Traditional and Herbal Medicine.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-
      1980-  Volume(issue)/page/year: 20,422,1989
 
                            *** END OF RECORD ***