*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE7670000
CHEMICAL NAME           : Benzo(h)cinnolin-3(2H)-one,
                          2-(4-(2-(dimethylamino)propoxy)phenyl)-9-fluoro-5,6-d
                          ihydro-, (E)-2-butenedioate
CAS REGISTRY NUMBER     : 123575-22-4
LAST UPDATED            : 199806
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C23-H24-F-N3-O2.C4-H4-O4
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   9-Fluoro-2-(4-(2-dimethylaminopropoxy)phenyl)-5,6-dihydrobenzo(h)cinnoli
     n-3(2H)-one fumarate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #5045541
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #5045541
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #5045541
 
                            *** END OF RECORD ***