*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE8396900
CHEMICAL NAME           : Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-6-ol,
                          5,6,7,8-tetrahydro-6,7-dimethyl-
                          1,2,3,13-tetramethoxy-, stereoisomer
CAS REGISTRY NUMBER     : 58546-54-6
OTHER CAS REGISTRY NOS. : 61281-39-8
LAST UPDATED            : 198910
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C23-H28-O7
MOLECULAR WEIGHT        : 416.51
SYNONYMS/TRADE NAMES :
   * Gomisin A
   * Schisandrol B
   * Schizandrol B
   * Wuweizi alcohol B
   * Wuweizichun B
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 777 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - somnolence (general depressed activity)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 101,1030,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 390 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - somnolence (general depressed activity)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 101,1030,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - somnolence (general depressed activity)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 101,1030,1981
 
                            *** END OF RECORD ***