*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE9350000
CHEMICAL NAME           : 3H-1,4-Benzodiazepine,
                          7-chloro-2-(methylamino)-5-phenyl-, 4-oxide and
                          barbituric acid, 5-ethyl-5-phenyl- (5:3)
CAS REGISTRY NUMBER     : 63917-56-6
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
WISWESSER LINE NOTATION : T67 GN JN IHJ CG HM1 JO KR &T6VMVMV FHJ F2 FR
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * Chlordiazepoxide and phenobarbital (5:3)
   * Phenobarbital and chlordiazepoxide (3:5)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - visual field changes
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   3,619,1961
 
                            *** END OF RECORD ***