*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF0525000
CHEMICAL NAME           : 2H-1,4-Benzodiazepin-2-one,
                          7-chloro-5-(1-cyclohexen-1-yl)-1,3-dihydro-1-methyl-
CAS REGISTRY NUMBER     : 10379-14-3
BEILSTEIN REFERENCE NO. : 0890548
REFERENCE               : 5-24-04-00064 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H17-Cl-N2-O
MOLECULAR WEIGHT        : 288.80
WISWESSER LINE NOTATION : T67 GNV JN IHJ CG G1 K- AL6UTJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * CB 4261
   * 4261 CB
   * 4361 CB
   *   7-Chloro-5-(cyclohexen-1-yl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2
     -one
   *   7-Chloro-5-(1-cyclohexenyl)-1-methyl-2-oxo-2,3-dihydro-1H-(1,4)-benzo(f)
     diazepine
   * Clinoxan
   * Musaril
   * Myolastan
   * Tetrazepam
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 2,254,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 415 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,171,1972
 
                            *** END OF RECORD ***