*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF2680000
CHEMICAL NAME           : 2H-1,5-Benzodiazepin-2-one,
                          5,5'-(1,3-dioxo-1,3-propanediyl)bis(1,3,4,5-tetrahydr
                          o-4-methyl-
CAS REGISTRY NUMBER     : 144400-96-4
LAST UPDATED            : 199403
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H24-N4-O4
MOLECULAR WEIGHT        : 420.51
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   5,5'-(1,3-Dioxo-1,3-propanediyl)bis(1,3,4,5-tetrahydro-4-methyl-2H-1,5-b
     enzodiazepin-2-one)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   43,495,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1170 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   43,495,1991
 
                            *** END OF RECORD ***