*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF2745500
CHEMICAL NAME           : 2H-1,5-Benzodiazepin-2-one,
                          1,3,4,5-tetrahydro-4-methyl-5-(1-oxo-2-butenyl)-
CAS REGISTRY NUMBER     : 144400-94-2
LAST UPDATED            : 199403
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H16-N2-O2
MOLECULAR WEIGHT        : 244.32
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1,3,4,5-Tetrahydro-4-methyl-5-(1-oxo-2-butenyl)-2H-1,5-benzodiazepin-2-o
     ne
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   43,495,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1451 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   43,495,1991
 
                            *** END OF RECORD ***