*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DE8267000
CHEMICAL NAME           : 5H-Benzocycloheptene-5-acetic acid,
                          6,7,8,9-tetrahydro-, (1-methyl-2-piperidinyl) methyl
                          ester
CAS REGISTRY NUMBER     : 40494-41-5
BEILSTEIN REFERENCE NO. : 1493187
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H29-N-O2
MOLECULAR WEIGHT        : 315.50
WISWESSER LINE NOTATION : L67&TJ G1VO1- BT6NTJ A1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6,7,8,9-Tetrahydro-5H-benzocycloheptene-5-acetic acid  
   (1-methyl-2-piperidinyl)methyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 22,2070,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 22,2070,1972
 
                            *** END OF RECORD ***