*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DF4935050 CHEMICAL NAME : 1,3-Benzodioxole, 5-(4-((2-pyrimidinyl)amino)piperidinomethyl)- CAS REGISTRY NUMBER : 76167-77-6 LAST UPDATED : 199112 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H20-N4-O2 MOLECULAR WEIGHT : 312.41 WISWESSER LINE NOTATION : T56 BO DO CHJ G1- AT6NTJ DM- BT6N CNJ COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 5-(4-((2-Pyrimidinyl)amino)piperidinomethyl)-1,3-benzodioxole *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >300 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Vascular - contraction (isolated tissues) REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,951,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >100 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Vascular - contraction (isolated tissues) REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,951,1980 *** END OF RECORD ***