*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DF4935400 CHEMICAL NAME : (1,3)Benzodioxolo(5,6-e)(2)benzazecin-14(6H)-one, 5,7,8,15-tetrahydro-3,4-dimethoxy-6- methyl-, monohydrochloride CAS REGISTRY NUMBER : 5569-36-8 LAST UPDATED : 198806 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H23-N-O5.Cl-H MOLECULAR WEIGHT : 405.91 WISWESSER LINE NOTATION : T F6 C-10-65 DV MN SO UO TH&T&&J IO1 JO1 M1 &GH SYNONYMS/TRADE NAMES : * Allocryptopine hydrochloride * alpha-Allocryptopine hydrochloride * alpha-Fagarine hydrochloride * beta-Homochelidonine hydrochloride * Thalictrimine hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 162 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 104,253,1952 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 34 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 123,269,1958 *** END OF RECORD ***