*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF4935400
CHEMICAL NAME           : (1,3)Benzodioxolo(5,6-e)(2)benzazecin-14(6H)-one,
                          5,7,8,15-tetrahydro-3,4-dimethoxy-6- methyl-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 5569-36-8
LAST UPDATED            : 198806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H23-N-O5.Cl-H
MOLECULAR WEIGHT        : 405.91
WISWESSER LINE NOTATION : T F6 C-10-65 DV MN SO UO TH&T&&J IO1 JO1 M1 &GH
SYNONYMS/TRADE NAMES :
   * Allocryptopine hydrochloride
   * alpha-Allocryptopine hydrochloride
   * alpha-Fagarine hydrochloride
   * beta-Homochelidonine hydrochloride
   * Thalictrimine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 162 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 104,253,1952
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 34 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 123,269,1958
 
                            *** END OF RECORD ***