*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DF4935500 CHEMICAL NAME : (1,3)-Benzodioxolo(5,6-c)phenanthridinium, 2,3-dimethoxy-12-methyl-, chloride CAS REGISTRY NUMBER : 13063-04-2 LAST UPDATED : 199410 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C21-H18-N-O4.Cl MOLECULAR WEIGHT : 383.85 WISWESSER LINE NOTATION : T G5 E6 B666 HO JO OK IHJ O1 SO1 TO1 &G COMPOUND DESCRIPTOR : Mutagen SYNONYMS/TRADE NAMES : * 2,3-Dimethoxy-12-methyl-(1,3)-benzodioxolo(5,6-c)phenanthridinium chloride * Nitidine chloride * NSC 146397 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 98980 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 40 ug/plate REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 66,1781,1977 *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Inconclusive: Histidine reversion-Ames test *** END OF RECORD ***