*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DF9485500
CHEMICAL NAME           : Benzo(a)heptalen-9(5H)-one,
                          6,7-dihydro-1,2,3,10-tetramethoxy-
CAS REGISTRY NUMBER     : 1420-08-2
BEILSTEIN REFERENCE NO. : 2016000
REFERENCE               : 4-08-00-03562 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H22-O5
MOLECULAR WEIGHT        : 342.42
WISWESSER LINE NOTATION : L B677 MV&T&J CO1 DO1 EO1 NO1
COMPOUND DESCRIPTOR     : Mutagen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Deacetamidocolchicine
   * Deacetylaminocolchicine
   * Desacetamidocolchicine
   * Desacetylaminocolchicine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 400 ug/kg
SEX/DURATION            : female 12-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 2,85,1970
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 190 nmol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   25,1383,1976
 
                            *** END OF RECORD ***