*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG1502000
CHEMICAL NAME           : Benzoic acid, 4-amino-3-butoxy-,
                          2-(diethylamino)ethyl ester
CAS REGISTRY NUMBER     : 99-43-4
BEILSTEIN REFERENCE NO. : 2288926
REFERENCE               : 4-14-00-02076 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C17-H28-N2-O3
MOLECULAR WEIGHT        : 308.47
WISWESSER LINE NOTATION : 4OR BZ EVO2N2&2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-Amino-3-n-butoxy-benzoesaeure-diaethylaminoaethylester
   * Benoxil
   * Benoxinate
   * Conjucain
   * 2-(Diethylamino)ethyl 4-amino-3-butoxybenzoate
   * Dorsacain
   * Novesinol
   * Oxibuprokain
   * Oxybucaine
   * Oxybuprocaine
   * Oxyriprocaine
   * Prescaina
   * S 749
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 37 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AACRAT Anesthesia and Analgesia (New York).  (Elsevier Science Pub. Co.,
   Inc., 52 Vanderbilt Ave., New York, NY 10017)  V.36-    1957-
   Volume(issue)/page/year: 38,265,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AACRAT Anesthesia and Analgesia (New York).  (Elsevier Science Pub. Co.,
   Inc., 52 Vanderbilt Ave., New York, NY 10017)  V.36-    1957-
   Volume(issue)/page/year: 38,265,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 3,612,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EESADV Ecotoxicology and Environmental Safety.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1977-  Volume(issue)/page/year:
   6,149,1982
 
                            *** END OF RECORD ***