*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG1502700
CHEMICAL NAME           : Benzoic acid, 4-amino-2-butoxy-,
                          2-(diethylamino)ethyl ester, hydrochloride
CAS REGISTRY NUMBER     : 15016-15-6
LAST UPDATED            : 199509
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C17-H28-N2-O3.Cl-H
MOLECULAR WEIGHT        : 344.93
WISWESSER LINE NOTATION : 2N2&2OVR DZ BO4 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-Amino-2-butoxy-benzoic acid 2-(diethylamino)ethyl ester hydrochloride
   * Benzoic acid, 4-amino-2-butoxy-, 2-(diethylamino)ethyl ester,  
   monohydrochloride
   * Sympocaine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 40,133,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4019 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 104,40,1952
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 24,1957,1974
 
                            *** END OF RECORD ***