*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG4285000
CHEMICAL NAME           : Benzoic acid, p-(3-(benzyloxy)-1H-indazol-1-yl)-,
                          butyl ester
CAS REGISTRY NUMBER     : 28570-58-3
BEILSTEIN REFERENCE NO. : 0857368
REFERENCE               : 5-23-11-00252 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H24-N2-O3
MOLECULAR WEIGHT        : 400.51
WISWESSER LINE NOTATION : T56 BNNJ BR DVO4& DO1R
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * p-(3-(Benzoyloxy)-1H-indazol-1-yl)benzoic acid butyl ester
   * ITF 636
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 24,965,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 810 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 24,965,1969
 
                            *** END OF RECORD ***