*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG3000000
CHEMICAL NAME           : Benzoic acid, p-amino-, 2-(pentylamino)ethyl ester
CAS REGISTRY NUMBER     : 2188-67-2
BEILSTEIN REFERENCE NO. : 2808234
REFERENCE               : 3-14-00-01040 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C14-H22-N2-O2
MOLECULAR WEIGHT        : 250.38
WISWESSER LINE NOTATION : ZR DVO2M5
SYNONYMS/TRADE NAMES :
   * p-Aminobenzoic acid 2-n-amylaminoethyl ester
   * p-Aminobenzoic acid 2-n-pentylaminoethyl ester
   * 2-n-Amylaminoethyl p-aminobenzoate
   * Amylcaine
   * Amylsine
   * Naepaine
   * 2-(Pentylamino)ethanol 4-aminobenzoate (ester)
   * 2-n-Pentylaminoethyl p-aminobenzoate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 62,69,1938
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 18 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle contraction or spasticity
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 62,69,1938
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 62,69,1938
 
                            *** END OF RECORD ***