*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG4996300
CHEMICAL NAME           : Benzoic acid,
                          2-chloro-5-(3,5-dimethylpiperidinosulfonyl)-
CAS REGISTRY NUMBER     : 24358-29-0
BEILSTEIN REFERENCE NO. : 1596377
REFERENCE               : 5-20-04-00192 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H18-Cl-N-O4-S
MOLECULAR WEIGHT        : 331.84
WISWESSER LINE NOTATION : T6NTJ ASWR DG CVQ& C1 E1
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 2-Chloro-5-(3,5-dimethylpiperidinosulphonyl)benzoic acid
   * Tibric acid
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 39 gm/kg/71W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   NATUAS Nature.  (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
   V.1-    1869-  Volume(issue)/page/year: 283,397,1980
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 500 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   40,36,1980
 
                            *** END OF RECORD ***