*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG5105000
CHEMICAL NAME           : Benzoic acid,
                          2-(7-chloro-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,
                          4-benzodiazepin-3-yl) hydrazide
CAS REGISTRY NUMBER     : 84044-26-8
LAST UPDATED            : 199803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C23-H19-Cl-N4-O2
MOLECULAR WEIGHT        : 418.91
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin-2-
     one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 16,617,1982
 
                            *** END OF RECORD ***