*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG3066000
CHEMICAL NAME           : Benzoic acid, 4-amino-2-propoxy-,
                          2-(diethylamino)ethyl ester, monohydrochloride
CAS REGISTRY NUMBER     : 550-83-4
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H26-N2-O3.Cl-H
MOLECULAR WEIGHT        : 330.90
WISWESSER LINE NOTATION : 3OR CZ FVO2N2&2 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-Amino-2-propoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride
   * Blockaine hydrochloride
   * Blockain hydrochloride
   * Pravocaine hydrochloride
   * Propoxycaine hydrochloride
   * Ravocaine hydrochloride
   * WIN 3459
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 40,133,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7417 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 123,269,1958
 
                            *** END OF RECORD ***