*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DG5658000
CHEMICAL NAME           : Benzoic acid,
                          3-((4-(3-cyclohexyl-3-hydroxy-1-propenyl)hexahydro-5-
                          hydroxy-2H-cyclopenta (b) furan-2-ylidene)methyl)-,
                          (3aR-(2Z,3a-alpha,4-alpha(1E,3S*),5-beta,6a-alpha))-
CAS REGISTRY NUMBER     : 108945-35-3
LAST UPDATED            : 199509
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H30-O5
MOLECULAR WEIGHT        : 398.54
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Taprostene
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 28 gm/kg/4W-I
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from small intestine
   Gastrointestinal - ulceration or bleeding from large intestine
   Gastrointestinal - other changes
REFERENCE :
   ETPAEK Experimental and Toxicologic Pathology.  (Gustav Fischer Verlag Jena,
   Postfach 100537, D-07705 Jena, Germany)  V.44-    1992-
   Volume(issue)/page/year: 46,71,1994
 
                            *** END OF RECORD ***