*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DG5775000 CHEMICAL NAME : Benzoic acid, p-(cyclohexyloxy)-, 3-(2-methylpiperidino)propyl ester, hydrochloride CAS REGISTRY NUMBER : 537-61-1 LAST UPDATED : 199404 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C22-H33-N-O3.Cl-H MOLECULAR WEIGHT : 396.02 WISWESSER LINE NOTATION : T6NTJ B1 A3OVR DO- AL6TJ &GH COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * p-Cyclohexyloxybenzoic acid 3-(2-methylpiperidino)propyl ester hydrochloride * Cyclomethycaine hydrochloride * N-(3-Hydroxypropyl)pipecoline hydrochloride p-cyclohexyloxybenzoic acid ester * 3-(2-Methylpiperidino)propyl p-(cyclo-hexyloxy)benzoate hydrochloride * 1-Piperidinepropanol, 2-methyl-, p-(cyclohexyloxy)benzoate, hydrochloride * Surfacaine hydrochloride * Surfathesin hydrochloride * Topocaine hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2340 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,37,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 447 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 68,2592,1946 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 54 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 68,2592,1946 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81535 No. of Facilities: 58 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 633 (estimated) *** END OF RECORD ***